5-HT7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14527

Novus Biologicals, part of Bio-Techne
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NBP3-14527
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Hamster (95%), Monkey (100%), Mouse (95%), Primate (100%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.6 mg/ml

View all 5-HT7 Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human 5HT7.

Epitope

N-Terminus

Reactivity Notes

Expected reactivity based on percent sequence identity: Equine (85%)

Specificity

Human 5-HT7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for 5-HT7 Antibody

Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]

Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]

Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527] - Immunohistochemistry of formalin-fixed, paraffin-embedded human cerebellum after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]

Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]

Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527] - Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, glioblastoma, after heat-induced antigen retrieval.

Applications for 5-HT7 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

0.6 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: 5-HT7

Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HTR1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). The 5-HT7 receptor (5-HT7R) is a seven-transmembrane-domain G-protein-coupled receptor that has important roles in regulating diverse biological process in the central and peripheral nervous systems (reviewed in Hedlund and Sutcliffe, 2004). Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HT1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). Sequence alignment shows a high degree of interspecies 5-HT7R homology (>90%), and a low homology with other 5-HTRs (

Long Name

5-Hydroxytryptamine Receptor 7

Alternate Names

5-HT-X, 5HT7, HTR7

Gene Symbol

HTR7

Additional 5-HT7 Products

Product Documents for 5-HT7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 5-HT7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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