58K Golgi Protein Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86031

Novus Biologicals, part of Bio-Techne
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NBP1-86031
NBP1-86031-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all 58K Golgi Protein Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MRLPKNIPEEKDRRTAALQEGLRRAVSVPLTLAETVASLWLALQELARCGNLACRSDLQVAAKALEMGVFGAYFNVLINLRDITDEAFKDQIHHRV

Marker

Golgi Apparatus Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for 58K Golgi Protein Antibody

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031]

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031]

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031] - Staining in human liver and pancreas tissues using anti-FTCD antibody. Corresponding FTCD RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031]

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031]

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031]

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031]

Immunohistochemistry-Paraffin: 58K Golgi Protein Antibody [NBP1-86031] - Staining of human liver shows high expression.

Applications for 58K Golgi Protein Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: 58K Golgi Protein

58K protein antibodies are excellent for use as markers for the Golgi complex. The 58K protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency; also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.

Alternate Names

formimidoyltransferase cyclodeaminase, formimidoyltransferase-cyclodeaminase, formiminotransferase cyclodeaminase, Formiminotransferase-cyclodeaminase, human formiminotransferase cyclodeaminase, EC 4.3.1.410formiminotransferase-cyclodeaminase, LCHC1

Gene Symbol

FTCD

Additional 58K Golgi Protein Products

Product Documents for 58K Golgi Protein Antibody

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Certificate of Analysis

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Product Specific Notices for 58K Golgi Protein Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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