A2BP1 Antibody (1G10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11943

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1G10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all A2BP1 Antibodies »

Product Specifications

Immunogen

Recombinant protein taken from the N-terminus of A2BP1 expressed in and purified from E. Coli. (UniProt: Q9NWB1)

Specificity

Specific for endogenous levels of the ~46/48 kD FOX1 protein doublet.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage).

Scientific Data Images for A2BP1 Antibody (1G10)

Western Blot: A2BP1 Antibody (1G10) [NBP3-11943]

Western Blot: A2BP1 Antibody (1G10) [NBP3-11943]

Western Blot: A2BP1 Antibody (1G10) [NBP3-11943] - Western blot of rat cortical lysate showing specific immunolabeling of the ~46/48 kDa A2BP1 protein.
Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody (1G10) [NBP3-11943]

Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody (1G10) [NBP3-11943]

Immunocytochemistry/Immunofluorescence: A2BP1 Antibody (1G10) [NBP3-11943] - Immunofluorescence of cultured rat neurons showing nuclear and distal cytoplasmic labeling of A2BP1 (cat. NBP3-11943, 1:500, green).

Applications for A2BP1 Antibody (1G10)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:500

Immunohistochemistry

1:500

Western Blot

1:5000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

100 ul in PBS

Preservative

0.07% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: A2BP1

Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. (provided by RefSeq)

Alternate Names

2BP1, A2BP, A2BP1 Hexaribonucleotide-binding protein 1, Ataxin-2-binding protein 1, FOX-1, FOX1 hexaribonucleotide binding protein 1, Fox-1 homolog A, HRNBP1 ataxin 2-binding protein 1, RNA binding protein fox-1 homolog 1, RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Symbol

RBFOX1

Additional A2BP1 Products

Product Documents for A2BP1 Antibody (1G10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for A2BP1 Antibody (1G10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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