ABCA7 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42095
Key Product Details
Species Reactivity
Human, Porcine
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit
Concentration
0.5 mg/ml
Product Specifications
Immunogen
Immunized with recombinant Human ABCA7 (Uniprot#: Q8IZY2; Glu53-Leu249 (Uniprot#: Q8IZY2)
Clonality
Polyclonal
Host
Rabbit
Applications for ABCA7 Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
5-20ug/mL
Immunohistochemistry
5-20ug/mL
Western Blot
0.5-2ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen and protein A Affinity-purified
Formulation
PBS, pH7.4, 50% glycerol
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: ABCA7
ABCA-7 is highly homologous to ABCA1, and also mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. It also may mediate cholesterol efflux.
ABCA7 antibodies are useful for studies of cholesterol formation and lipid processing mechanisms.
Alternate Names
ABCA-SSN, ABCXATP-binding cassette sub-family A member 7, ATP-binding cassette, sub-family A (ABC1), member 7, Autoantigen SS-N, EC 2.2.1.1, EC 3.6.3, EC 3.6.3.41, FLJ40025, Macrophage ABC transporter
Gene Symbol
ABCA7
Additional ABCA7 Products
Product Documents for ABCA7 Antibody
Product Specific Notices for ABCA7 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Loading...
Loading...
Loading...
Loading...