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ABCB11 Antibody (BSEP/7534)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26754

Novus Biologicals, part of Bio-Techne
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NBP3-26754-100ug
NBP3-26754-20ug

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # BSEP/7534

Concentration

0.2 mg/ml

Product Summary for ABCB11 Antibody (BSEP/7534)

Immunogen

Recombinant fragment (around aa600-800) of human ABCB11 protein (exact sequence is proprietary)

Localization

Membrane

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Description

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for ABCB11 Antibody (BSEP/7534)

ABCB11 Antibody (BSEP/7534)

Immunohistochemistry-Paraffin: ABCB11 Antibody (BSEP/7534) [NBP3-26754 ] -

Formalin-fixed, paraffin-embedded human liver stained with ABCB11 Antibody (BSEP/7534). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
ABCB11 Antibody (BSEP/7534)

Western Blot: ABCB11 Antibody (BSEP/7534) [NBP3-26754 ] -

Western blot analysis of THP-1 cell lysate using ABCB11 Antibody (BSEP/7534).

Applications for ABCB11 Antibody (BSEP/7534)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml for 30 minutes at RT

Western Blot

1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: ABCB11

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. (provided by RefSeq)

Alternate Names

ABC member 16, MDR/TAP subfamily, ABC16, ATP-binding cassette sub-family B member 11, ATP-binding cassette, sub-family B (MDR/TAP), member 11, bile salt export pump, BSEP, BSEPPFIC2, EC 3.6.3, EC 3.6.3.44, PFIC-2, PGY4, progressive familial intrahepatic cholestasis 2, sister p-glycoprotein, SPGPBRIC2

Gene Symbol

ABCB11

Additional ABCB11 Products

Product Documents for ABCB11 Antibody (BSEP/7534)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ABCB11 Antibody (BSEP/7534)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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