Sterol O-acyltransferase 1 (SOAT1), also known as ACAT1, catalyzes the formation of intracellular cholesterol esters in various tissues, such as adult human liver, adrenal glands, macrophages, and kidneys. Specifically, ACAT-1 catalyzes the reversible reaction forming acetoacetyl-CoA from two molecules of acetyl-CoA. Additionaly, the ACAT 1 protein may have a role in lipoprotein assembly and dietary cholesterol absorption, and may also act as a ligase.

Mutations in this gene have been associated with 3-ketothiolase deficiency, an inborn defect of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Long Name

Acetyl-CoA Acetyltransferase 1

Alternate Names

THIL

Gene Symbol

ACAT1

Additional ACAT1 Products

Product Documents for ACAT1 Antibody (2C5) [mFluor Violet 610 SE]

Product Datasheets

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COA

SDS

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Product Specific Notices for ACAT1 Antibody (2C5) [mFluor Violet 610 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ACAT1 Antibody (2C5) [mFluor Violet 610 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22565MFV610

Key Product Details

Species Reactivity

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Product Specifications

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Applications for ACAT1 Antibody (2C5) [mFluor Violet 610 SE]

ELISA

Immunocytochemistry/ Immunofluorescence

Western Blot

Formulation, Preparation, and Storage

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Background: ACAT1