ACTH Antibody (CLIP/7197R)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23601
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # CLIP/7197R
Concentration
0.2 mg/ml
Product Specifications
Immunogen
N-terminal fragment of human ACTH conjugated to KLH
Reactivity Notes
Expected to show a broad species reactivity.
Localization
Cytoplasm. Secreted.
Specificity
This monoclonal antibody is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
Marker
Pituitary Marker
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Description
Store at 2 to 8C. Non-hazardous. No MSDS required.
Scientific Data Images for ACTH Antibody (CLIP/7197R)
Immunohistochemistry-Paraffin: ACTH Antibody (CLIP/7197R) [NBP3-23601] -
Formalin-fixed, paraffin-embedded human pituitary gland stained with ACTH antibody (CLIP/7197R). HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.Applications for ACTH Antibody (CLIP/7197R)
Application
Recommended Usage
Immunohistochemistry-Paraffin
1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: ACTH
Long Name
Adrenocorticotropic Hormone
Alternate Names
Adrenocorticotropin, Corticotropin
Gene Symbol
POMC
Additional ACTH Products
Product Documents for ACTH Antibody (CLIP/7197R)
Product Specific Notices for ACTH Antibody (CLIP/7197R)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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