ADAM2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85416

Novus Biologicals, part of Bio-Techne
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NBP1-85416
NBP1-85416-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ADAM2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NVSYGIEPLESSVGFEHVIYQVKHKKADVSLYNEKDIESRDLSFKLQSVEPQQDFAKYIEMHVIVEKQLYNHMGSDTTVVAQKVFQLIGLTNAI

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 26252478).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ADAM2 Antibody

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416]

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416]

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416] - Staining in human testis and liver tissues using anti-ADAM2 antibody. Corresponding ADAM2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416]

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416]

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416]

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416]

Immunohistochemistry-Paraffin: ADAM2 Antibody [NBP1-85416] - Staining of human testis shows high expression.

Applications for ADAM2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
IHC reported in scientific literature (PMID: 26252478). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ADAM2

ADAM2, or Disintegrin and metalloproteinase domain-containing protein 2, contains a 82 kDa and a 80 kDa isoform, and is involved in the adhesion of the sperm-egg membrane during fertilization. Current research is being conducted to determine the relationship between ADAM2 and a variety of disorders and diseases, including infertility, epidiymitis, Alzheimer's disease, and reflex sympathetic dystrophy. ADAM2 has been linked to the integrin-mediated signaling pathway and processes involving cellular adhesion, through which it interacts with CD9, CLGN, CRYAB, DNM1, and ITGA9.

Long Name

A Disintegrin and Metalloproteinase Domain 2

Alternate Names

CT15, Fertilin beta, PH-30, PH30, PH30-beta

Gene Symbol

ADAM2

Additional ADAM2 Products

Product Documents for ADAM2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ADAM2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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