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ADAM9 Antibody (Imgc936) - Humanized

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28228

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Imgc936

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

ADAM9

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 147.46 kDa.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ADAM9 Antibody (Imgc936) - Humanized

ADAM9 Antibody (Imgc936) - Humanized

Functional: ADAM9 Antibody (Imgc936) - Humanized[NBP3-28228] -

The endocytosis ratio Imgc936 by Human ADAM9 HT29 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 50% at antibody concentration of 1 nM.
ADAM9 Antibody (Imgc936) - Humanized

Flow Cytometry: ADAM9 Antibody (Imgc936) - Humanized[NBP3-28228] -

Human ADAM9 CHOS cells were stained with ADAM9 Antibody (Imgc936) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.3912 nM.

Applications for ADAM9 Antibody (Imgc936) - Humanized

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: ADAM9

ADAM9 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.

Long Name

A Disintegrin and Metalloprotease-like Domain 9

Alternate Names

MCMP, MDC9, Meltrin gamma

Gene Symbol

ADAM9

UniProt

Additional ADAM9 Products

Product Documents for ADAM9 Antibody (Imgc936) - Humanized

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ADAM9 Antibody (Imgc936) - Humanized

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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