ADAMTS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89246

Novus Biologicals, part of Bio-Techne
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NBP1-89246
NBP1-89246-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ADAMTS2 Antibodies »

Product Summary for ADAMTS2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VAMEVRPSPSTPLEVPLNASSTNATEDHPETNAVDEPYKIHGLEDEVQPSNLIPRRPSPYEKTRNQRIQELIDEMRKKEMLG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ADAMTS2 Antibody

Immunocytochemistry/ Immunofluorescence: ADAMTS2 Antibody [NBP1-89246]

Immunocytochemistry/ Immunofluorescence: ADAMTS2 Antibody [NBP1-89246]

Immunocytochemistry/Immunofluorescence: ADAMTS2 Antibody [NBP1-89246] - Staining of human cell line BJ shows localization to plasma membrane & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: ADAMTS2 Antibody [NBP1-89246]

Immunohistochemistry-Paraffin: ADAMTS2 Antibody [NBP1-89246]

Immunohistochemistry-Paraffin: ADAMTS2 Antibody [NBP1-89246] - Staining of human skin shows weak to moderate cytoplasmic positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: ADAMTS2 Antibody [NBP1-89246]

Immunohistochemistry-Paraffin: ADAMTS2 Antibody [NBP1-89246]

Immunohistochemistry-Paraffin: ADAMTS2 Antibody [NBP1-89246] - Staining of human endometrium shows moderate cytoplasmic positivity in glandular cells.
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Applications for ADAMTS2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ADAMTS2

ADAMTS2 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.

Long Name

A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 2

Alternate Names

ADAMTS-2, EDSDERMS, HPCPNI, PC I-NP, PCINP, PCPNI

Gene Symbol

ADAMTS2

Additional ADAMTS2 Products

Product Documents for ADAMTS2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ADAMTS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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