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Adenovirus Hexon Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB600-1386

Novus Biologicals, part of Bio-Techne
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NB600-1386
NB600-1386-0.1ml

Key Product Details

Species Reactivity

Virus

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

4.0 mg/ml

Product Specifications

Immunogen

Gradient purified, disrupted native adenovirus type 5 virions

Reactivity Notes

Cross-reacts with Adenovirus. Does not react with Para 1-3, Influenza A and B, or RSV.

Localization

Major coat protein of adenoviruses.

Specificity

Recognizes numerous Adeno proteins including hexon protein, and reacts with Adenovirus types 1, 2, 3, 5, 6, 7a, 8, 31, 40 & 41. Broad reactivity with other Adenovirus types is expected. Goat anti Adenovirus antibody does not cross-react with Parainfluenza types 1-3, Influenza A & B, RSV, hMPV and Rhinovirus type 16. Goat anti Adenovirus antibody does not react with uninfected Hep-2, LLCMK2 and Vero cells. Adenoviruses are 80-110 nm diameter, non-enveloped icosahedral viruses that can cause respiratory illness, infantile gastroenteritis and other mild disorders such as conjunctivitis. Features of Adenovirus have made it a useful tool for gene transfection and expression in mammalian cells.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Adenovirus Hexon Antibody

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

4.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Adenovirus Hexon

Hexon protein is a major coat protein of adenoviruses. Adenoviruses capsids have three principal protein components: the hexon, the penton, and the fiber. Hexon consists of three subunits together forming two major components of different morphological symmetry. A triangular top with three towers of density is superimposed on a more bulky pseudo hexagonal base. The symmetry of the top is in accord with the trimeric nature of hexon, but that of the base derives from the molecular function, which is to provide a densely packed impenetrable protective outer layer for the virion.

Alternate Names

Hexon protein; Late protein 2; PII

Additional Adenovirus Hexon Products

Product Documents for Adenovirus Hexon Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Adenovirus Hexon Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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