Adenylate Cyclase 6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-75180

Novus Biologicals, part of Bio-Techne
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NB100-75180
NB100-75180-0.025mg
NB100-75180-0.02mg
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Adenylate Cyclase 6 Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody was a sequence from 1a.a. to 121a.a. from Adenylate cyclase type 6(a 1168a.a. long protein)

Reactivity Notes

This antibody is reactive against Human.

Localization

Membrane; multi-pass membrane protein.

Specificity

Adenylate Cyclase 6

Clonality

Polyclonal

Host

Chicken

Scientific Data Images for Adenylate Cyclase 6 Antibody

Western Blot: Adenylate Cyclase 6 Antibody [NB100-75180]

Western Blot: Adenylate Cyclase 6 Antibody [NB100-75180]

Western Blot: E coli-derived fusion protein as test antigen. Affi-anti-ATP7A IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-ADCY6)

Applications for Adenylate Cyclase 6 Antibody

Application
Recommended Usage

Western Blot

1:200-1:500
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affi-anti-ATP7A IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Adenylate Cyclase 6

The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein-coupled receptors. Eight human AC isoforms (AC1 through AC4), encoded by separate genes, have been identified up to now. Most of the adenylate cyclase genes are comprise of 11-26 exons and distributed over a q6-430 kb. Majority of the adenylate cyclases previously described are expressed discretely in defined peripheral tissues, the type 4 adenylate cyclase (AC4) is apparently expressed in a variety of peripheral tissues and in the central nervous system, mainly in olfactory system. AC5 is localized on photoreceptor cells and are also designated as GC1 and GC2. The AC5 protein resembles the other adenylyl cyclases in its predicted and proposed structure. AC5 resembles the type 6 (AC6) adenylyl cyclase in its amino acid sequence but becomes divergent at N and C-terminal ends. The AC5 and AC6 proteins are co-localized in most of the visual organs (photoreceptor cells) are associated with other protein complexes. Both AC5 and AC6 enzymes play an important role in synaptic plasticity by coordinating overlapping synaptic inputs from Gs and Gi coupled receptor stimulation. Membrane-bound. calcium-inhibitable adenylyl cyclase (By similarity).

Long Name

Adenylate cyclase type 6

Alternate Names

ADCY6, Adenylyl cyclase 6, KIAA0422

Entrez Gene IDs

112 (Human)

Gene Symbol

ADCY6

UniProt

O43306 (Human)

Additional Adenylate Cyclase 6 Products

Product Documents for Adenylate Cyclase 6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Adenylate Cyclase 6 Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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