AGER Antibody (CL10587)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07982

Novus Biologicals, part of Bio-Techne
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NBP3-07982-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL10587

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RAGE/AGER Antibodies »

Product Summary for AGER Antibody (CL10587)

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids: VSEGSYPAGTLSWHLDGK

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for AGER Antibody (CL10587)

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982]

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982]

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982] - Analysis in human lung and prostate tissues using NBP3-07982 antibody. Corresponding AGER RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982]

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982]

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982] - Staining of human prostate shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982]

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982]

Immunohistochemistry-Paraffin: AGER Antibody (CL10587) [NBP3-07982] - Staining of human kidney shows no positivity in cells in tubules as expected.
View 3 more images

Applications for AGER Antibody (CL10587)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RAGE/AGER

AGER encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Long Name

Receptor for Advanced Glycation End Products

Alternate Names

AGER, SCARJ1

Gene Symbol

AGER

Additional RAGE/AGER Products

Product Documents for AGER Antibody (CL10587)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AGER Antibody (CL10587)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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