AGXT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89199

Novus Biologicals, part of Bio-Techne
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NBP1-89199
NBP1-89199-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AGXT2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DVRGKGLMIGIEMVQDKISCRPLPREEVNQIHEDCKHMGLLVGRGSIFSQTFRIAPSMCITKPEVDFAVEVFRSALTQHMERRAK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (85%). Reactivity reported in scientific literature (PMID: 24586340).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AGXT2 Antibody

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199]

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199]

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199] - Staining in human kidney and lymph node tissues using anti-AGXT2 antibody. Corresponding AGXT2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199]

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199]

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199] - Staining of human kidney shows high expression.
Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199]

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199]

Immunohistochemistry-Paraffin: AGXT2 Antibody [NBP1-89199] - Staining of human lymph node shows low expression as expected.

Applications for AGXT2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, WB reactvity reported in (PMID: 24586340).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AGXT2

AGXT2, also known as Alanin-glyoxylate aminotransferase 2, consists of a 524 amino acid isoform that is 57 kDa, and is involved in the conversion of glyoxylate to glycine, the digestion of asymmetric dimethylarginine, and the regulation of blood pressure. Current research is being conducted on AGXT2 and its relation to mycobacterium tuberculosis and primary hyperoxaluria. This protein is included in the pathways of nucleotide and pyrimidine metabolism where it interacts with AGXT, ALAS2, GATM, GCAT, and GLDC.

Alternate Names

(R)-3-amino-2-methylpropionate--pyruvate transaminase, AGT 2, alanine-glyoxylate aminotransferase 2, alanine--glyoxylate aminotransferase 2, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, DAIBAT, D-AIBAT, EC 2.6.1.40, EC 2.6.1.44, mitochondrial

Entrez Gene IDs

64902 (Human)

Gene Symbol

AGXT2

UniProt

Q9BYV1 (Human)

Additional AGXT2 Products

Product Documents for AGXT2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AGXT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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