ALDH5A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32970

Novus Biologicals, part of Bio-Techne
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NBP1-32970
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ALDH5A1 Antibodies »

Product Summary for ALDH5A1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human ALDH5A1. The exact sequence is proprietary.

Reactivity Notes

Mouse reactivity determined by WB.

Localization

Mitochondrion

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALDH5A1 Antibody

Western Blot: ALDH5A1 Antibody [NBP1-32970]

Western Blot: ALDH5A1 Antibody [NBP1-32970]

Western Blot: ALDH5A1 Antibody [NBP1-32970] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: ALDH5A1 Antibody [NBP1-32970]

Immunocytochemistry/ Immunofluorescence: ALDH5A1 Antibody [NBP1-32970]

Immunocytochemistry/Immunofluorescence: ALDH5A1 Antibody [NBP1-32970] - Analysis of methanol-fixed A431, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: ALDH5A1 Antibody [NBP1-32970]

Immunohistochemistry-Paraffin: ALDH5A1 Antibody [NBP1-32970]

Immunohistochemistry-Paraffin: ALDH5A1 Antibody [NBP1-32970] - ALDH5A1 antibody detects ALDH5A1 protein at mitochondria in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. ALDH5A1 antibody diluted at 1:500.
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Applications for ALDH5A1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ALDH5A1

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternate Names

aldehyde dehydrogenase 5 family, member A1, EC 1.2.1, EC 1.2.1.24, NAD(+)-dependent succinic semialdehyde dehydrogenase, SSADHmitochondrial

Gene Symbol

ALDH5A1

Additional ALDH5A1 Products

Product Documents for ALDH5A1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ALDH5A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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