ALDH6A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52101

Novus Biologicals, part of Bio-Techne
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NBP1-52101
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all ALDH6A1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SRSSFRGDTN corresponding to internal region according to NP_005580.1.

Epitope

C-SRSSFRGDTN

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ALDH6A1 Antibody

Western Blot: ALDH6A1 Antibody [NBP1-52101]

Western Blot: ALDH6A1 Antibody [NBP1-52101]

Western Blot: ALDH6A1 Antibody [NBP1-52101] - Analysis of ALDH6A1 in Mouse Kidney lysate (35ug protein in RIPA buffer) using this antibody at 0.1 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for ALDH6A1 Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 55 kDa band observed in human, mouse and rat kidney lysates (calculated MW of 57.8 kDa band according to NP_005580.1). IHC-P: Human liver shows textured staining of the cytoplasm consistent with mitochondria.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ALDH6A1

This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Alternate Names

aldehyde dehydrogenase 6 family, member A1, Aldehyde dehydrogenase family 6 member A1, EC 1.2.1.18, EC 1.2.1.27, malonate-semialdehyde dehydrogenase, Malonate-semialdehyde dehydrogenase [acylating], methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MGC40271, MMSADHA, MMSDHmitochondrial acylating methylmalonate-semialdehyde dehydrogenase

Entrez Gene IDs

4329 (Human); 104776 (Mouse); 81708 (Rat)

Gene Symbol

ALDH6A1

UniProt

NP_005580.1 (Human)

Additional ALDH6A1 Products

Product Documents for ALDH6A1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ALDH6A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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