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ALK-7/Activin Receptor Type 1C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90253

Novus Biologicals, part of Bio-Techne
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NBP1-90253
NBP1-90253-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ALK-7/Activin Receptor Type 1C Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALK-7/Activin Receptor Type 1C Antibody

Immunohistochemistry-Paraffin: ALK-7/Activin Receptor Type 1C Antibody [NBP1-90253]

Immunohistochemistry-Paraffin: ALK-7/Activin Receptor Type 1C Antibody [NBP1-90253]

Immunohistochemistry-Paraffin: ALK-7/Activin Receptor Type 1C Antibody [NBP1-90253] - Staining of human prostate shows strong cytoplasmic positivity in glandular cells.

Applications for ALK-7/Activin Receptor Type 1C Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALK-7

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type Ireceptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interactdirectly with DNA or in complex with other transcription factors (Bondestam et al., 2001 (PubMed 12063393)).(suppliedby OMIM)

Long Name

Activin Receptor-like Kinase 7

Alternate Names

Activin RIC, ACVR1C, ACVRLK7, ALK7

Gene Symbol

ACVR1C

Additional ALK-7 Products

Product Documents for ALK-7/Activin Receptor Type 1C Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ALK-7/Activin Receptor Type 1C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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