alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS697

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey, Primate

Cited:

Human, Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all alpha-1B Adrenergic R/ADRA1B Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from C-terminus of human alpha-1B Adrenergic R/ADRA1B.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Bat (85%), Opossum (80%), Platypus (80%).

Specificity

Human ADRA1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PLEKHG5 (45%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free

Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free [NLS697]

Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free [NLS697]

Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody [NLS697] - Analysis of anti-ADRA1B antibody with human adrenal, medulla.

Applications for alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

11 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: alpha-1B Adrenergic R/ADRA1B

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

Long Name

Alpha-1B Adrenergic Receptor

Alternate Names

a-1B AdrenergicR, ADRA1B, alpha1B AdrenergicR, ALPHA1BAR

Entrez Gene IDs

147 (Human)

Gene Symbol

ADRA1B

UniProt

P35368

Additional alpha-1B Adrenergic R/ADRA1B Products

Product Documents for alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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