alpha Desmuslin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37892

Novus Biologicals, part of Bio-Techne
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NBP2-37892
NBP2-37892-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all alpha Desmuslin Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: FLGSGYSSSATTQQENSYGKAVSSQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVAAGASESTRSNE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for alpha Desmuslin Antibody

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892]

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892]

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892] - Analysis in human skeletal muscle and liver tissues using NBP2-37892 antibody. Corresponding SYNM RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892]

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892]

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892] - Staining of human heart muscle, liver, prostate and skeletal muscle using Anti-SYNM antibody NBP2-37892 (A) shows similar protein distribution across tissues to independent antibody NBP2-37909 (B).
Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892]

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892]

Immunohistochemistry-Paraffin: alpha Desmuslin Antibody [NBP2-37892] - Staining of human prostate shows strong cytoplasmic positivity in smooth muscle cells.
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Applications for alpha Desmuslin Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha Desmuslin

alpha Desmuslin is encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene.

Alternate Names

desmuslin, DMNEC 1.4.99.1, EC 2.6.1.16, KIAA0353synemin beta, SYNDesmuslin, synemin, synemin alpha, synemin, intermediate filament protein

Gene Symbol

SYNM

UniProt

O15061 (Human)

Additional alpha Desmuslin Products

Product Documents for alpha Desmuslin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha Desmuslin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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