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Alpha Fodrin Antibody (AA6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-42321

Novus Biologicals, part of Bio-Techne
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NBP1-42321

Key Product Details

Species Reactivity

Human, Rat, Chicken, Guinea Pig, Rabbit

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # AA6

Concentration

0.1 mg/ml

Product Specifications

Immunogen

Chicken red blood cell membranes purified by hypotonic lysis and mechanical enucleation

Specificity

Specific to the 240 kD a-fodrin molecule of all mammalian nonerythroid cells and chicken a-spectrin.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Alpha Fodrin Antibody (AA6)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Western Blot

1:1000
Application Notes
Immunohistochemical stainings on frozen sections, western blotting and other immunoassays for cellular and tumor biology.Working dilution in western blotting is at least 1:1000.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, 1% BSA

Preservative

0.1% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Alpha Fodrin

SPTAN1/Alpha II-spectrin is one of two polypeptide chains (alpha and beta) that are part of the fodrin tetramer. Fodrin functions to link actin filaments to the plasma membrane and is a major neuronal cytoskeletal protein. Fodrin has been linked to neurogenerative and autoimmune diseases. Alternate names for SPTAN1/Alpha II-spectrin include alpha-fodrin, spectrin alpha chain brain, spectrin non-erythroid alpha chain, fodrin alpha chain, SPTA2, and FLJ44613.

Alternate Names

Alpha-II spectrin, EIEE5, FLJ17738, FLJ44613, Fodrin alpha chain, NEAS, spectrin alpha chain, brain, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spectrin, non-erythroid alpha chain, SPTA2

Gene Symbol

SPTAN1

Additional Alpha Fodrin Products

Product Documents for Alpha Fodrin Antibody (AA6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Alpha Fodrin Antibody (AA6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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