Alpha Fodrin Antibody (SPTAN1/3506)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13782

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # SPTAN1/3506

Concentration

0.2 mg/ml

View all Alpha Fodrin Antibodies »

Product Summary for Alpha Fodrin Antibody (SPTAN1/3506)

Immunogen

Recombinant fragment of human Alpha Fodrin protein (around aa2351-2475) (exact sequence is proprietary)) (Uniprot: Q13813)

Localization

Cytoplasm

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

240 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14185)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for Alpha Fodrin Antibody (SPTAN1/3506)

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782]

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782]

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782] - Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with Alpha Fodrin antibody (SPTAN1/3506).
Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782]

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782]

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782] - Formalin-fixed, paraffin-embedded human placenta stained with Alpha Fodrin antibody (SPTAN1/3506).
Protein Array: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782]

Protein Array: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782]

Protein Array: Alpha Fodrin Antibody (SPTAN1/3506) [NBP3-13782] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Alpha Fodrin Antibody (SPTAN1/3506).

Applications for Alpha Fodrin Antibody (SPTAN1/3506)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Alpha Fodrin

SPTAN1/Alpha II-spectrin is one of two polypeptide chains (alpha and beta) that are part of the fodrin tetramer. Fodrin functions to link actin filaments to the plasma membrane and is a major neuronal cytoskeletal protein. Fodrin has been linked to neurogenerative and autoimmune diseases.

Alternate Names

Alpha-II spectrin, EIEE5, FLJ17738, FLJ44613, Fodrin alpha chain, NEAS, spectrin alpha chain, brain, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spectrin, non-erythroid alpha chain, SPTA2

Gene Symbol

SPTAN1

UniProt

Q13813 (Human)

Additional Alpha Fodrin Products

Product Documents for Alpha Fodrin Antibody (SPTAN1/3506)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Alpha Fodrin Antibody (SPTAN1/3506)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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