Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunoprecipitation (Negative), Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all Alpha Fodrin Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1000 and 1050 of human spectrin, alpha, non-erythrocytic 1 using the numbering given in entry NP_003118.1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Alpha Fodrin Antibody - BSA Free

Western Blot: Alpha Fodrin Antibody [NB100-60441]

Western Blot: Alpha Fodrin Antibody [NB100-60441]

Western Blot: Alpha Fodrin Antibody [NB100-60441] - Whole cell lysate from HeLa (5, 15 and 50 ug), 293T (T; 50 ug), and mouse NIH3T3 (M; 50 ug) cells. Antibody used at for WB at 0.2 ug/ml.
Immunohistochemistry: Alpha Fodrin Antibody [NB100-60441]

Immunohistochemistry: Alpha Fodrin Antibody [NB100-60441]

Immunohistochemistry: Alpha Fodrin Antibody [NB100-60441] - Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti- SPTAN1/Alpha II-Spectrin used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Applications for Alpha Fodrin Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:2000-1:10000
Application Notes
This antibody is useful for Western Blot analysis. It is not recommended for Immunoprecipitation.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Alpha Fodrin

SPTAN1/Alpha II-spectrin is one of two polypeptide chains (alpha and beta) that are part of the fodrin tetramer. Fodrin functions to link actin filaments to the plasma membrane and is a major neuronal cytoskeletal protein. Fodrin has been linked to neurogenerative and autoimmune diseases. Alternate names for SPTAN1/Alpha II-spectrin include alpha-fodrin, spectrin alpha chain brain, spectrin non-erythroid alpha chain, fodrin alpha chain, SPTA2, and FLJ44613.

Alternate Names

Alpha-II spectrin, EIEE5, FLJ17738, FLJ44613, Fodrin alpha chain, NEAS, spectrin alpha chain, brain, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spectrin, non-erythroid alpha chain, SPTA2

Entrez Gene IDs

6709 (Human); 20740 (Mouse)

Gene Symbol

SPTAN1

UniProt

Q13813 (Human)

Additional Alpha Fodrin Products

Product Documents for Alpha Fodrin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Alpha Fodrin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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