alpha-L-Iduronidase/IDUA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10781

Novus Biologicals, part of Bio-Techne
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NBP3-10781-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all alpha-L-Iduronidase/IDUA Antibodies »

Product Summary for alpha-L-Iduronidase/IDUA Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human alpha-L-Iduronidase/IDUA. Peptide sequence LAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRL

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for alpha-L-Iduronidase/IDUA Antibody

Western Blot: alpha-L-Iduronidase/IDUA Antibody [NBP3-10781]

Western Blot: alpha-L-Iduronidase/IDUA Antibody [NBP3-10781]

Western Blot: alpha-L-Iduronidase/IDUA Antibody [NBP3-10781] - Western blot analysis of alpha-L-Iduronidase/IDUA in 293T Whole Cell lysates. Antibody dilution at 1.0ug/ml

Applications for alpha-L-Iduronidase/IDUA Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-L-Iduronidase/IDUA

alpha-L-Iduronidase, encoded by the IDUA gene, is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non-reducing terminal a-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue, and organ damage.

Alternate Names

alphaLIduronidase, IDA, IDUA

Gene Symbol

IDUA

Additional alpha-L-Iduronidase/IDUA Products

Product Documents for alpha-L-Iduronidase/IDUA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for alpha-L-Iduronidase/IDUA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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