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Aminopeptidase A/ENPEP Antibody (2G11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15176

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15176

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2G11

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human Aminopeptidase A/ENPEP. UniProt ID (Q07075).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Aminopeptidase A/ENPEP Antibody (2G11)

Immunohistochemistry: Aminopeptidase A/ENPEP Antibody (2G11) [NBP3-15176]

Immunohistochemistry: Aminopeptidase A/ENPEP Antibody (2G11) [NBP3-15176]

Immunohistochemistry: Aminopeptidase A/ENPEP Antibody (2G11) [NBP3-15176] - IHC image of Aminopeptidase A/ENPEP antibody diluted at 1:100 and staining in paraffin-embedded human kidney tissue. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Applications for Aminopeptidase A/ENPEP Antibody (2G11)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Aminopeptidase A/ENPEP

Aminopeptidase A is a zinc-dependent metallopeptidase that selectively cleaves N-terminal Glu, or Asp residues from peptides. In mice, it is expressed on early B cells and on a subset of thymic cortical epithelial cells, but not on mature lymphocytes. Additionally, it is expressed on endothelial cells, intestinal epithelium, proximal renal tubules, and other non-hemopoietic tissues. In humans, angiotensin II is the the best-defined biologically active substrate of APA. Although its role in the immune response is still uncertain, its expression on renal cell carcinoma has been the focus of some cancer research studies.

Alternate Names

CD249, ENPEP

Gene Symbol

ENPEP

Additional Aminopeptidase A/ENPEP Products

Product Documents for Aminopeptidase A/ENPEP Antibody (2G11)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Aminopeptidase A/ENPEP Antibody (2G11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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