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Aminopeptidase A/ENPEP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85774

Novus Biologicals, part of Bio-Techne
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NBP1-85774
NBP1-85774-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Aminopeptidase A/ENPEP Antibody

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774]

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774]

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774] - Staining of human stomach shows low expression as expected.
Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774]

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774]

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774] - Staining of human small intestine shows high expression.
Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774]

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774]

Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774] - Staining in human small intestine and stomach tissues using anti-ENPEP antibody. Corresponding ENPEP RNA-seq data are presented for the same tissues.

Applications for Aminopeptidase A/ENPEP Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Aminopeptidase A/ENPEP

Aminopeptidase A is a zinc-dependent metallopeptidase that selectively cleaves N-terminal Glu, or Asp residues from peptides. In mice, it is expressed on early B cells and on a subset of thymic cortical epithelial cells, but not on mature lymphocytes. Additionally, it is expressed on endothelial cells, intestinal epithelium, proximal renal tubules, and other non-hemopoietic tissues. In humans, angiotensin II is the the best-defined biologically active substrate of APA. Although its role in the immune response is still uncertain, its expression on renal cell carcinoma has been the focus of some cancer research studies.

Alternate Names

CD249, ENPEP

Gene Symbol

ENPEP

Additional Aminopeptidase A/ENPEP Products

Product Documents for Aminopeptidase A/ENPEP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Aminopeptidase A/ENPEP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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