Amnionless/AMN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98805

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Amnionless Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human Amnionless/AMN.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Amnionless/AMN Antibody

Immunohistochemistry-Paraffin: Amnionless/AMN Antibody [NBP2-98805]

Immunohistochemistry-Paraffin: Amnionless/AMN Antibody [NBP2-98805]

Immunohistochemistry-Paraffin: Amnionless/AMN Antibody [NBP2-98805] - Immunochemical staining of human Amnionless/AMN in human kidney with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

Applications for Amnionless/AMN Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Amnionless

AMN is type I transmembrane protein that is required for surface expression of the extracellular membrane-associated protein, cubilin. The two form a complex termed CUBAM in which AMN mediates endocytosis of compounds bound by cubulin. AMN is required for embryonic primitive streak formation in the mouse, and is highly expressed on adult polarized epithelia in the small intestine and kidney proximal convoluted tubules. Mutations of AMN or cubilin cause Imersund-Grasbeck syndrome, also called megaloblastic anemia-1, characterized by malabsorption of cobalamin (vitamin B12).

Alternate Names

AMN

Gene Symbol

AMN

Additional Amnionless Products

Product Documents for Amnionless/AMN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Amnionless/AMN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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