Angiopoietin-4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30090

Novus Biologicals, part of Bio-Techne
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NBP1-30090
NBP1-30090-0.025mg
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Key Product Details

Species Reactivity

Human, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Angiopoietin-4 Antibodies »

Product Specifications

Immunogen

Synthetic peptide (CPPGPEVSRDSNTLQRESLANPLHLGKLPTQQV) corresponding to aa 55-87 of human Angiopoietin 4.

Epitope

aa 55-87

Reactivity Notes

Human and Macaque

Specificity

Sequence Similarity: CPPGPEVSRDSNTLQRESLANPLHLGKLPTQQV 55-87. Human NP-057069 EASRDSNTLQRESLANPLRLEKLPTQQV 60-87 Macaque

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Angiopoietin-4 Antibody

Immunohistochemistry: Angiopoietin-4 Antibody [NBP1-30090]

Immunohistochemistry: Angiopoietin-4 Antibody [NBP1-30090]

Immunohistochemistry: Angiopoietin-4 Antibody [NBP1-30090] - Antibody to human angiopoietin4 on paraffin section of human liver (above), and of human lung (below)

Applications for Angiopoietin-4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -80C. Avoid freeze-thaw cycles.

Background: Angiopoietin-4

Angiopoietin 3 (ANG3), also called ANG4, might represent counterparts in mouse and human. Based on chromosomal analysis, mouse ANG3 is thought to be an ortholog of human ANG4. Human ANG4 acts as an agonist that binds and activates Tie2, whereas mouse ANG3 is likely to be a Tie2 antagonist, exerting agonist or antagonist activities depending on the cell context. Mouse ANG3 is expressed in various mouse tissues. Mouse angiopoietin 3 is a secreted glycoprotein and member of the angiopoietin family. It has an N terminal coiled-coil domain and a Cbterminal fibrinogen like domain. The coiled coil domains mediate ligand homo oligomerization and the fibrinogen like domains mediate ligand activity. Recombinant mouse angiopoietin 3 has a calculated molecular mass of 58 kDa. Due to glycosylation, the recombinant protein (containing 3 peptides) has an apparent molecular mass of 85-90 kDa in SDS-PAGE under reducing conditions. Mouse angiopoietin 3 shares 47%, 46%, and 54% sequence identity with mouse ANG1, mouse ANG2, and human ANG4, respectively.

Alternate Names

ANGPT4

Entrez Gene IDs

51378 (Human)

Gene Symbol

ANGPT4

Additional Angiopoietin-4 Products

Product Documents for Angiopoietin-4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Angiopoietin-4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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