APCDD1 Antibody [PerCP]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-92756PCP

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB110-92756AF350

Alexa Fluor 405

NB110-92756AF405

Alexa Fluor 488

NB110-92756AF488

Alexa Fluor 532

NB110-92756AF532

Alexa Fluor 594

NB110-92756AF594

Alexa Fluor 647

NB110-92756AF647

Alexa Fluor 700

NB110-92756AF700

Alexa Fluor 750

NB110-92756AF750

Allophycocyanin

NB110-92756APC

Biotin

NB110-92756B

CoraFluor 1

NB110-92756CL1

DyLight 350

NB110-92756UV

DyLight 405

NB110-92756V

DyLight 488

NB110-92756G

DyLight 550

NB110-92756R

DyLight 594

NB110-92756DL594

DyLight 650

NB110-92756C

DyLight 680

NB110-92756FR

DyLight 755

NB110-92756IR

HRP

NB110-92756H

Janelia Fluor 525

NB110-92756JF525

Janelia Fluor 549

NB110-92756JF549

Janelia Fluor 646

NB110-92756JF646

Janelia Fluor 669

NB110-92756JF669

mFluor Violet 450 SE

NB110-92756MFV450

mFluor Violet 500 SE

NB110-92756MFV500

mFluor Violet 610 SE

NB110-92756MFV610

PE

NB110-92756PE

Forumulation

Catalog #

BSA Free

NB110-92756

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Chicken, Reptile

Applications

Knockdown Validated, Western Blot

Label

PerCP (Excitation = 490 nm, Emission = 675 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all APCDD1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide made to an internal portion of human APCDD1 (within residues 400-500). [Swiss-Prot# Q8J025]

Reactivity Notes

Turtle.

Localization

Membrane.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for APCDD1 Antibody [PerCP]

Application

Recommended Usage

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: APCDD1

Adenomatosis polyposis coli down-regulated 1 protein (APCDD1), also known as DRAPC1, is a negative regulator of the Wnt signaling pathway. APCDD1 acts to inhibit Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin interaction. APCDD-1 is most strongly expressed in pancreas, heart, prostate, ovary, lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. APCDD1 is expressed in both the epidermal and dermal compartments of the hair follicle, and in the dermal papilla, the matrix, and the hair shaft. Mutations in the APCDD1 gene cause hypotrichosis simplex (HTS), a rare form of non-syndromic hereditary hypotrichosis characterized by progressive hairloss in early childhood. The APCDD1 protein has also been found overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1-mutated Wilms tumors.

APCDD1 antibodies may be useful for hair loss studies and research on certian cancers.

Long Name

APC Down Regulated 1

Alternate Names

APC Down Regulated 1, DRAPC1, HYPT1

Gene Symbol

APCDD1

Additional APCDD1 Products

Product Documents for APCDD1 Antibody [PerCP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for APCDD1 Antibody [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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