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APLP-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89036

Novus Biologicals, part of Bio-Techne
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NBP1-89036
NBP1-89036-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for APLP-1 Antibody

Immunohistochemistry-Paraffin: APLP-1 Antibody [NBP1-89036]

Immunohistochemistry-Paraffin: APLP-1 Antibody [NBP1-89036]

Immunohistochemistry-Paraffin: APLP-1 Antibody [NBP1-89036] - Staining in human cerebral cortex and liver tissues using anti-APLP1 antibody. Corresponding APLP1 RNA-seq data are presented for the same tissues.
Western Blot: APLP-1 Antibody [NBP1-89036]

Western Blot: APLP-1 Antibody [NBP1-89036]

Western Blot: APLP-1 Antibody [NBP1-89036] - Analysis in control (vector only transfected HEK293T lysate) and APLP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: APLP-1 Antibody [NBP1-89036]

Immunohistochemistry-Paraffin: APLP-1 Antibody [NBP1-89036]

Immunohistochemistry-Paraffin: APLP-1 Antibody [NBP1-89036] - Staining of human liver shows no positivity in hepatocytes as expected.

Applications for APLP-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APLP-1

APLP1, or Amyloid-like protein 1, contains two similar isoforms weighing approximately 72 kDa each, and is involved in postsynaptic function and signal transduction activation. Disease research is currently being conducted on APLP1 and its relation to chronic fatigue syndrome, lissencephaly, neuronitis, infertility, neurodegeneration, pharyngitis, cerebritis, and neuroblastoma. The protein is not linked to specific pathways, but it does interact with ZNF24, TK1, TSC22D1, EEF1A1, and GDF9.

Long Name

Amyloid-like Protein 1

Alternate Names

APLP1

Gene Symbol

APLP1

Additional APLP-1 Products

Product Documents for APLP-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for APLP-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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