Apolipoprotein A5 Antibody (C11)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41491
Key Product Details
Species Reactivity
Human
Applications
ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2b Kappa Clone # C11
Concentration
1 mg/ml
Product Specifications
Immunogen
Immunized with recombinant Human Apolipoprotein A5 (Uniprot#: Q6Q788; Asp167-Lys335 (Uniprot#: Q6Q788)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2b Kappa
Scientific Data Images for Apolipoprotein A5 Antibody (C11)
Immunohistochemistry-Paraffin: Apolipoprotein A5 Antibody (C11) [NBP3-41491] -
Immunohistochemistry-Paraffin: Apolipoprotein A5 Antibody (C11) [NBP3-41491] - DAB staining on IHC-P; Samples: Human Lung Tissue; Primary Ab: 30ug/ml NBP3-41491
Western Blot: Apolipoprotein A5 Antibody (C11) [NBP3-41491] -
Western Blot: Apolipoprotein A5 Antibody (C11) [NBP3-41491] - Sample: Recombinant protein.Applications for Apolipoprotein A5 Antibody (C11)
Application
Recommended Usage
ELISA
0.05-2ug/ml
Immunocytochemistry/ Immunofluorescence
5-30ug/ml
Immunohistochemistry-Frozen
5-30ug/ml
Immunohistochemistry-Paraffin
5-30ug/ml
Western Blot
0.5-5ug/ml
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS, pH7.4, 50% glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Apolipoprotein A5
Apo A5 is expressed in the plasma and the liver, where it is involved in the early phase of liver regeneration.
APOA5 mutations can lead to increaased susceptibility to familial hypertriglyceridemia (FHTR), a common inherited disorder where VLDL concentrations are elevated in the plasma. This disorder increases the risk of heart disease, obesity, and pancreatitis. APOA5 mutations can also cause hyperlipoproteinemia type 5 (HLPP5), characterized by increased amounts of chylomicrons/VLDL and decreased amounts of LDL/HDL in the plasma. This disorder often leads to a wide array of syndromes, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A
ApoA5 antibodies are useful for studying lipoprotein processing and a variety of cardiac diseases.
Alternate Names
APOAV, apo-AV, APOA-V, Apolipoprotein A5, apolipoprotein A-V, FLJ97995, MGC126836, RAP3MGC126838, Regeneration-associated protein 3
Gene Symbol
APOA5
Additional Apolipoprotein A5 Products
Product Documents for Apolipoprotein A5 Antibody (C11)
Product Specific Notices for Apolipoprotein A5 Antibody (C11)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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