APPL Antibody (S05-8D5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14998

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-8D5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all APPL Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human APPL (Uniprot#: Q9UKG1)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for APPL Antibody (S05-8D5)

Western Blot: APPL Antibody (S05-8D5) [NBP3-14998]

Western Blot: APPL Antibody (S05-8D5) [NBP3-14998]

Western Blot: APPL Antibody (S05-8D5) [NBP3-14998] - Western blot detection of APPL in Rat Brain, C6, 3T3, Hela cell lysates using APPL Rabbit mAb (1:1000 diluted). Predicted band size: 80kDa. Observed band size: 80kDa.
Immunohistochemistry-Paraffin: APPL Antibody (S05-8D5) [NBP3-14998]

Immunohistochemistry-Paraffin: APPL Antibody (S05-8D5) [NBP3-14998]

Immunohistochemistry-Paraffin: APPL Antibody (S05-8D5) [NBP3-14998] - Immunohistochemistry of APPL in paraffin-embedded Human lung cancer tissue using APPL Rabbit mAb at dilution 1/20

Applications for APPL Antibody (S05-8D5)

Application
Recommended Usage

Immunohistochemistry

1/20

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APPL

APPL is encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Long Name

Adapter Protein Containing PH Domain PTB Domain and Leucine Zipper Motif 1

Alternate Names

APPL1, DIP13A

Gene Symbol

APPL1

Additional APPL Products

Product Documents for APPL Antibody (S05-8D5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for APPL Antibody (S05-8D5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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