APPL Products
APPL, also known as DCC interacting protein 13 alpha (DIP13 alpha), is a widely expressed approximately 80 kDa intracellular adaptor protein. APPL contains two coiled-coil domains (aa 215-259 and aa 621-673), a pleckstrin homology domain (aa 277-375) and a phosphotyrosine interaction domain (PID) (aa 496-656). These domains and the cytoplasmic and nuclear localization of APPL enable it to associate with a range of molecules involved in multiple pathways. APPL mediates the insulin-sensitizing and anti-inflammatory effects of adiponectin through direct interactions with AdipoR1 and AdipoR2.
45 results for "APPL" in Products
45 results for "APPL" in Products
APPL Products
APPL, also known as DCC interacting protein 13 alpha (DIP13 alpha), is a widely expressed approximately 80 kDa intracellular adaptor protein. APPL contains two coiled-coil domains (aa 215-259 and aa 621-673), a pleckstrin homology domain (aa 277-375) and a phosphotyrosine interaction domain (PID) (aa 496-656). These domains and the cytoplasmic and nuclear localization of APPL enable it to associate with a range of molecules involved in multiple pathways. APPL mediates the insulin-sensitizing and anti-inflammatory effects of adiponectin through direct interactions with AdipoR1 and AdipoR2.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #709208 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC, WB |
![Western Blot: APPL Antibody (OTI4B11) [NBP2-46536]](https://resources.bio-techne.com/images/products/APPL-Antibody-OTI4B11-Western-Blot-NBP2-46536-img0001.jpg "Western Blot: APPL Antibody (OTI4B11) [NBP2-46536]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: APPL Antibody [NBP2-15434]](https://resources.bio-techne.com/images/products/APPL-Antibody-Western-Blot-NBP2-15434-img0002.jpg "Western Blot: APPL Antibody [NBP2-15434]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S05-8D5 |
| Applications: | IHC, WB |
![Western Blot: APPL Antibody (S05-8D5) [NBP3-14998]](https://resources.bio-techne.com/images/products/APPL-Antibody-S05-8D5-Western-Blot-NBP3-14998-img0001.jpg "Western Blot: APPL Antibody (S05-8D5) [NBP3-14998]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: APPL Antibody [NBP2-15433]](https://resources.bio-techne.com/images/products/APPL-Antibody-Western-Blot-NBP2-15433-img0002.jpg "Western Blot: APPL Antibody [NBP2-15433]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: APPL Antibody [NB100-57841]](https://resources.bio-techne.com/images/products/APPL-Antibody-Western-Blot-NB100-57841-img0002.jpg "Western Blot: APPL Antibody [NB100-57841]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #4M5X9 |
| Applications: | WB |
![Western Blot: APPL Antibody (4M5X9) [NBP3-16721]](https://resources.bio-techne.com/images/products/APPL-Antibody-4M5X9-Western-Blot-NBP3-16721-img0001.jpg "Western Blot: APPL Antibody (4M5X9) [NBP3-16721]")
| Applications: | WB |
![Western Blot: APPL Overexpression Lysate [NBL1-07633]](https://resources.bio-techne.com/images/products/APPL-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-07633-img0002.jpg "Western Blot: APPL Overexpression Lysate [NBL1-07633]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: APPL Antibody [NBP2-76565]](https://resources.bio-techne.com/images/products/APPL-Antibody-Western-Blot-NBP2-76565-img0001.jpg "Western Blot: APPL Antibody [NBP2-76565]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: APPL Antibody [NBP1-90123]](https://resources.bio-techne.com/images/products/APPL-Antibody-Immunohistochemistry-NBP1-90123-img0003.jpg "Immunohistochemistry-Paraffin: APPL Antibody [NBP1-90123]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B11 |
| Applications: | IHC |