ARHGEF11 Antibody (2F4)

Novus Biologicals, part of Bio-Techne | Catalog # H00009826-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2F4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARHGEF11 Antibodies »

Product Specifications

Immunogen

ARHGEF11 (AAH57394, 651 a.a. ~ 750 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEATRLHQSASSSTSSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDTLLPHLLEDDLGQLSDLEPE

Reactivity Notes

Human. Other species not tested.

Specificity

ARHGEF11 - Rho guanine nucleotide exchange factor (GEF) 11

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for ARHGEF11 Antibody (2F4)

Western Blot: ARHGEF11 Antibody (2F4) [H00009826-M02]

Western Blot: ARHGEF11 Antibody (2F4) [H00009826-M02]

Western Blot: ARHGEF11 Antibody (2F4) [H00009826-M02] - ARHGEF11 monoclonal antibody (M02), clone 2F4. Analysis of ARHGEF11 expression in human colon.
Sandwich ELISA: ARHGEF11 Antibody (2F4) [H00009826-M02] - Detection limit for recombinant GST tagged ARHGEF11 is approximately 0.3ng/ml as a capture antibody.

Applications for ARHGEF11 Antibody (2F4)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ARHGEF11

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Alternate Names

DKFZp667F1223, glutamate transporter EAAT4-associated protein 48, GTRAP48, KIAA0380rho guanine nucleotide exchange factor 11, PDZ-RhoGEF, Rho guanine exchange factor (GEF) 11, Rho guanine nucleotide exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator

Entrez Gene IDs

9826 (Human)

Gene Symbol

ARHGEF11

OMIM

605708 (Human)

UniProt

AAH57394 (Human)

Additional ARHGEF11 Products

Product Documents for ARHGEF11 Antibody (2F4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ARHGEF11 Antibody (2F4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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