ARHGEF11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83314

Novus Biologicals, part of Bio-Techne
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NBP1-83314
NBP1-83314-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Chicken

Cited:

Avian - Chicken

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARHGEF11 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LQAEIDSRLRNSEDARGVLCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLDLDGDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLREARPSNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKEQDA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%). . Chicken reactivity reported in scientific literature (PMID: 25812521).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARHGEF11 Antibody

Western Blot: ARHGEF11 Antibody [NBP1-83314]

Western Blot: ARHGEF11 Antibody [NBP1-83314]

Western Blot: ARHGEF11 Antibody [NBP1-83314] - Analysis in control (vector only transfected HEK293T lysate) and ARHGEF11 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP1-83314]

Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP1-83314]

Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP1-83314] - Staining of human colon.
Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP1-83314]

Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP1-83314]

Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP1-83314] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.
View 4 more images

Applications for ARHGEF11 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARHGEF11

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq]

Alternate Names

DKFZp667F1223, glutamate transporter EAAT4-associated protein 48, GTRAP48, KIAA0380rho guanine nucleotide exchange factor 11, PDZ-RhoGEF, Rho guanine exchange factor (GEF) 11, Rho guanine nucleotide exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator

Gene Symbol

ARHGEF11

Additional ARHGEF11 Products

Product Documents for ARHGEF11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ARHGEF11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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