Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all ARVCF Antibodies »

Product Specifications

Immunogen

The immunogen for this product maps to a region between residue 75 and 125 of human Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome using the numbering given in entry NP_001661.1 (GeneID 421).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARVCF Antibody

Western Blot: ARVCF Antibody [NBP1-78213]

Western Blot: ARVCF Antibody [NBP1-78213]

Western Blot: ARVCF Antibody [NBP1-78213] - Whole cell lysate from Jurkat (15 and 50 ug), 293T (T; 50 ug) and HeLa (H; 50 ug) cells. Antibody used at 1 ug/ml.

Applications for ARVCF Antibody

Application
Recommended Usage

Western Blot

1:500-1:2500

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ARVCF

Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family which play an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS) a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.

Alternate Names

armadillo repeat gene deleted in velocardiofacial syndrome, armadillo repeat protein deleted in velo-cardio-facial syndrome, FLJ35345

Gene Symbol

ARVCF

UniProt

NP_001661.1 (Human)

Additional ARVCF Products

Product Documents for ARVCF Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARVCF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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