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ASB8 Antibody (1H1)

Novus Biologicals, part of Bio-Techne | Catalog # H00140461-M05

Novus Biologicals, part of Bio-Techne
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H00140461-M05

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1H1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

ASB8 (NP_077000, 179 a.a. ~ 288 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VINLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE

Specificity

ASB8 - ankyrin repeat and SOCS box-containing 8 (1H1)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for ASB8 Antibody (1H1)

Immunohistochemistry-Paraffin: ASB8 Antibody (1H1) [H00140461-M05]

Immunohistochemistry-Paraffin: ASB8 Antibody (1H1) [H00140461-M05]

Immunohistochemistry-Paraffin: ASB8 Antibody (1H1) [H00140461-M05] - Analysis of monoclonal antibody to ASB8 on formalin-fixed paraffin-embedded human pancreas. Antibody concentration 3 ug/ml
Sandwich ELISA: ASB8 Antibody (1H1) [H00140461-M05] - Detection limit for recombinant GST tagged ASB8 is 3 ng/ml as a capture antibody.

Applications for ASB8 Antibody (1H1)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This product is useful for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ASB8

ASB8 (Ankyrin repeat and SOCS box protein 8) is a 288 amino acid protein that has its highest level of expression in skeletal muscle. It is also expressed in heart, brain, placenta, liver, kidney and pancreas. ASB8 contains a SOCS box domain suggesting that it may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It also contains 4 ankyrin repeats which mediate protein-protein interactions and are among the most common structural motifs in known proteins.

Alternate Names

ankyrin repeat and SOCS box containing 8, ankyrin repeat and SOCS box protein 8, ankyrin repeat and SOCS box-containing 8, ASB-8, FLJ21255, MGC5540

Entrez Gene IDs

140461 (Human)

Gene Symbol

ASB8

Additional ASB8 Products

Product Documents for ASB8 Antibody (1H1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ASB8 Antibody (1H1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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