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ASCL1/Mash1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17687

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-17687-100ul
NBP3-17687-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ASCL1/Mash1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ASCL1/Mash1 Antibody

Immunocytochemistry/ Immunofluorescence: ASCL1/Mash1 Antibody [NBP3-17687]

Immunocytochemistry/ Immunofluorescence: ASCL1/Mash1 Antibody [NBP3-17687]

Immunocytochemistry/Immunofluorescence: ASCL1/Mash1 Antibody [NBP3-17687] - Staining of human cell line SH-SY5Y shows localization to nucleoplasm.

Applications for ASCL1/Mash1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence, PFA/Triton X-100 is recommended for fixation/permeabilization.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ASCL1/Mash1

MASH1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

Long Name

Achaete Scute Complex-like 1

Alternate Names

ASCL1, ASH1, HASH1, Mash1

Gene Symbol

ASCL1

Additional ASCL1/Mash1 Products

Product Documents for ASCL1/Mash1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ASCL1/Mash1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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