ASP/C3a desArg Antibody (2991)

Novus Biologicals, part of Bio-Techne | Catalog # NB600-1210

Novus Biologicals, part of Bio-Techne
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NB600-1210
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Key Product Details

Species Reactivity

Human

Applications

Immunoassay, Sandwich ELISA Detection, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2991

Concentration

0.1 mg/ml

View all ASP/C3a desArg Antibodies »

Product Specifications

Immunogen

Human C3a des-Arg

Specificity

This reacts with a neo-epitope (des-Arg) on C3a that is formed when C3 is cleaved into C3a and C3b.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for ASP/C3a desArg Antibody (2991)

Immunoassay: ASP/C3a desArg Antibody (2991) [NB600-1210]

Immunoassay: ASP/C3a desArg Antibody (2991) [NB600-1210]

Immunoassay: ASP/C3a desArg Antibody (2991) [NB600-1210] - Three different batches tested in a sandwich ELISAto determine the specificity of clone 2991 (used as detection antibody)

Applications for ASP/C3a desArg Antibody (2991)

Application
Recommended Usage

Western Blot

1:50-1:2000
Application Notes
WB: A reduced sample treatment and SDS-PAGE was used. The band size is ~8 kDa .

Reviewed Applications

Read 1 review rated 5 using NB600-1210 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.1% BSA

Preservative

0.02% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: ASP/C3a desArg

Acylation-stimulating protein (ASP), also known as C3adesArg, is an approximately 14 kDa member of the complement family that plays a role in the regulation of triglyceride synthesis (1-4). The secreted protein is a polypeptide fragment comprising amino acids (aa) 672-747 of the Complement C3 precursor protein (4). The polypeptide results from desargination of the carboxyl terminus of C3a, which is generated from interactions among C3, factor B, and adipsin (4). ASP contains a 36 aa anaphylatoxin-like domain (5). Human ASP shares 68% sequence identity with mouse and rat ASP. Increased levels of ASP are usually associated with insulin resistance, obesity and diabetes. It promotes triacylglycerol synthesis in adipocytes and inflammatory cytokine production in a septic environment (6-8).

Long Name

Acylation Stimulating Protein

Alternate Names

C3a des Arg

Entrez Gene IDs

718 (Human)

Gene Symbol

C3

UniProt

P01024

Additional ASP/C3a desArg Products

Product Documents for ASP/C3a desArg Antibody (2991)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ASP/C3a desArg Antibody (2991)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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