Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all ASXL2 Antibodies »

Product Summary for ASXL2 Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 600 and 650 of human additional sex combs like 2 using the numbering given in entry NP_060733.4 (GeneID 55252).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ASXL2 Antibody

Western Blot: ASXL2 Antibody [NBP1-18926]

Western Blot: ASXL2 Antibody [NBP1-18926]

Western Blot: ASXL2 Antibody [NBP1-18926] - Whole cell lysate from HeLa cells. ASXL2 was also immunoprecipitated by another rabbit anti-ASXL2 antibody.

Applications for ASXL2 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ASXL2

The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML). Alternate names for ASXL2 include ASXH2 and KIAA1685.

Alternate Names

additional sex combs like 2 (Drosophila), Additional sex combs-like protein 2, ASXH2polycomb group protein ASXH2, FLJ10898, KIAA1685DKFZp686C1968, putative Polycomb group protein ASXL2

Entrez Gene IDs

55252 (Human)

Gene Symbol

ASXL2

UniProt

Q76L83 (Human)

Additional ASXL2 Products

Product Documents for ASXL2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ASXL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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