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ATF3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87050

Novus Biologicals, part of Bio-Techne
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NBP2-87050

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ATF3. Peptide sequence: PLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEK The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ATF3 Antibody

Western Blot: ATF3 Antibody [NBP2-87050]

Western Blot: ATF3 Antibody [NBP2-87050]

Western Blot: ATF3 Antibody [NBP2-87050] - Host: Rabbit. Target: ATF3. Positive control (+): Human liver (LI). Negative control (-): Stomach tumor (T-ST). Antibody concentration: 3ug/ml
Western Blot: ATF3 Antibody [NBP2-87050]

Western Blot: ATF3 Antibody [NBP2-87050]

Western Blot: ATF3 Antibody [NBP2-87050] - Host: Rabbit. Target Name: ATF3. Sample Tissue: Human Jurkat Whole Cell. Antibody Dilution: 1ug/ml
Western Blot: ATF3 Antibody [NBP2-87050]

Western Blot: ATF3 Antibody [NBP2-87050]

Western Blot: ATF3 Antibody [NBP2-87050] - Host: Rabbit. Target Name: ATF3. Sample Tissue: Human 293T. Antibody Dilution: 1.0ug/ml

Applications for ATF3 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATF3

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

Alternate Names

activating transcription factor 3cAMP-dependent transcription factor ATF-3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cyclic AMP-dependent transcription factor ATF-3

Gene Symbol

ATF3

Additional ATF3 Products

Product Documents for ATF3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ATF3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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