ATG12 Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76860B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-76860AF350

Alexa Fluor 405

NBP1-76860AF405

Alexa Fluor 488

NBP1-76860AF488

Alexa Fluor 532

NBP1-76860AF532

Alexa Fluor 594

NBP1-76860AF594

Alexa Fluor 647

NBP1-76860AF647

Alexa Fluor 700

NBP1-76860AF700

Alexa Fluor 750

NBP1-76860AF750

CoraFluor 1

NBP1-76860CL1

DyLight 350

NBP1-76860UV

DyLight 405

NBP1-76860V

DyLight 488

NBP1-76860G

DyLight 550

NBP1-76860R

DyLight 594

NBP1-76860DL594

DyLight 650

NBP1-76860C

DyLight 680

NBP1-76860FR

DyLight 755

NBP1-76860IR

FITC

NBP1-76860F

HRP

NBP1-76860H

Janelia Fluor 525

NBP1-76860JF525

Janelia Fluor 549

NBP1-76860JF549

Janelia Fluor 585

NBP1-76860JF585

Janelia Fluor 635

NBP1-76860JF635

Janelia Fluor 646

NBP1-76860JF646

Janelia Fluor 669

NBP1-76860JF669

mFluor Violet 450 SE

NBP1-76860MFV450

mFluor Violet 500 SE

NBP1-76860MFV500

mFluor Violet 610 SE

NBP1-76860MFV610

PerCP

NBP1-76860PCP

Forumulation

Catalog #

BSA Free

NBP1-76860

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ATG12 Antibodies »

Product Summary for ATG12 Antibody [Biotin]

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ATG12. The immunogen is located within the first 50 amino acids of ATG12. Amino Acid Squence: CDAPWRKARPLHALSR

Reactivity Notes

0

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for ATG12 Antibody [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ATG12

The ATG12 gene codes a ubiquitin-like protein ATG12 that in isoform 1 is 140 amino acids long at 15 kDA and in isoform 2 is 74 amino acids long at 7 kDA. This protein is critical for autophagy (bulk protein degradation) as it is the human homolog of a yeast protein that participates in autophagy. ATG12 participates in the immune system, apoptosis and autophagy, protein stability, negative regulators of RIG-I/MDA5 signaling, and glucose/energy metabolism. It is known to interact with various genes such as HIST1H2BF, HIST1H2BE, HIST1H2BI, HIST1H2BG, and HIST1H2BC. ATG12 has been researched regarding its role in leukemia, lung cancer, myositis, retinitis, carcinoma, colorectal cancer, and myelodysplastic syndrome.

Long Name

ATG12 Autophagy Related 12 Homolog

Alternate Names

APG12, FBR93, HAPG12

Gene Symbol

ATG12

Additional ATG12 Products

Product Documents for ATG12 Antibody [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ATG12 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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