ATP13A2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-41486

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Simple Western, Western Blot

Cited:

IF/IHC, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.75 mg/ml

View all ATP13A2 Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an internal region of the human ATP13A2 protein (within residues 200-300). [Swiss-Prot# Q9NQ11]

Localization

Membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ATP13A2 Antibody

Western Blot: ATP13A2 Antibody [NB110-41486]

Western Blot: ATP13A2 Antibody [NB110-41486]

Western Blot: ATP13A2 Antibody [NB110-41486] - Detection of ATP13A2 in mouse brain membrane lysate.
Immunohistochemistry: ATP13A2 Antibody [NB110-41486]

Immunohistochemistry: ATP13A2 Antibody [NB110-41486]

Immunohistochemistry: ATP13A2 Antibody [NB110-41486] - Staining of neurons and neuropils using a concentration of 10ug/ml. Human brain, 40X.
Simple Western: ATP13A2 Antibody [NB110-41486]

Simple Western: ATP13A2 Antibody [NB110-41486]

Simple Western: ATP13A2 Antibody [NB110-41486] - Simple Western lane view shows a specific band for ATP13A2 in 0.5 mg/ml of Human Brain lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Applications for ATP13A2 Antibody

Application
Recommended Usage

Immunohistochemistry

10 ug/ml

Simple Western

1:100

Western Blot

2ug/ ml
Application Notes
This ATP13A2 antibody is useful for Immunohistochemistry and Western Blot.

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Glycine and 0.15M NaCl

Preservative

0.05% Sodium Azide

Concentration

0.75 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ATP13A2

Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders. ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia. ATP13A2 protein is located in the membrane of these lysosomes and is formed most strongly in the brain, especially in the substantia nigra, a brain region which is known to play a central role in Parkinsons disease.

Alternate Names

ATPase type 13A2, EC 3.6.3, EC 3.6.3.-, EC 3.6.3.5, EC 3.6.3.8, FLJ26510, HSA9947, KRPPD, PARK9putative ATPase, Parkinson disease (autosomal recessive) 9 (Kufor-Rakeb syndrome), probable cation-transporting ATPase 13A2

Gene Symbol

ATP13A2

Additional ATP13A2 Products

Product Documents for ATP13A2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ATP13A2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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