ATP7b Antibody (SR1205)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22667

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22667-100ul
NBP3-22667-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1205

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ATP7b Antibodies »

Product Summary for ATP7b Antibody (SR1205)

Immunogen

A synthesized peptide derived from human ATP7b (Uniprot #: P35670)

Specificity

Detects endogenous levels of total ATP7b

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

157 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ATP7b Antibody (SR1205)

ATP7b Antibody (SR1205)

Western Blot-NBP3-22667-ATP7b Antibody (SR1205)-

Western Blot-NBP3-22667-ATP7b Antibody (SR1205)-Analysis of ATP7b expression in HepG2 cell lysate.

Applications for ATP7b Antibody (SR1205)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATP7b

ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; form A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.

Alternate Names

ATPase, Cu(2+)- transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide, Copper pump 2, copper-transporting ATPase 2, EC 3.6.3, EC 3.6.3.4, PWD, WC1, WD, Wilson disease-associated protein, WNDATPase, Cu++ transporting, beta polypeptide (Wilson disease)

Gene Symbol

ATP7B

Additional ATP7b Products

Product Documents for ATP7b Antibody (SR1205)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ATP7b Antibody (SR1205)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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