Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2B7

Concentration

0.74 mg/ml

View all Aurora C Antibodies »

Product Specifications

Immunogen

Full-length protein expressed in 293T cell transfected with human AURKC expression vector

Specificity

This antibody is specific for Homo sapiens aurora kinase C (AURKC), transcript variant 1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

35.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Aurora C Antibody (OTI2B7)

Western Blot: Aurora C Antibody (OTI2B7) [NBP1-47663]

Western Blot: Aurora C Antibody (OTI2B7) [NBP1-47663]

Western Blot: Aurora C Antibody (2B7) [NBP1-47663] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Aurora C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Aurora C.
Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] Staining of paraffin-embedded prostate tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (OTI2B7) [NBP1-47663]

Immunohistochemistry-Paraffin: Aurora C Antibody (OTI2B7) [NBP1-47663]

Immunohistochemistry-Paraffin: Aurora C Antibody (2B7) [NBP1-47663] - Staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-Aurora C mouse monoclonal antibody.
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Applications for Aurora C Antibody (OTI2B7)

Application
Recommended Usage

Immunohistochemistry

1:50

Immunohistochemistry-Paraffin

1:50

Western Blot

1:200-1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.74 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Aurora C

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Long Name

Aurora kinase C

Alternate Names

AIE2, AIK3, AIRK3, ARK-3, ARK3, AURKC, Aurora 3, EC 2.7.11.1, STK13

Entrez Gene IDs

6795 (Human)

Gene Symbol

AURKC

Additional Aurora C Products

Product Documents for Aurora C Antibody (OTI2B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Aurora C Antibody (OTI2B7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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