Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Axin-1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1. The immunogen is located within amino acids 620 - 670 of AXIN1. Amino Acid Squence: EKEISRHRRTGHGS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Axin-1 Antibody - BSA Free

Axin-1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Axin-1 Antibody - BSA Free [NBP1-76483] -

Immunocytochemistry/ Immunofluorescence: Axin-1 Antibody - BSA Free [NBP1-76483] - Immunofluorescence of Axin-1 in human brain tissue with Axin-1 antibody at 20 u/mL.
Western Blot: Axin-1 AntibodyBSA Free [NBP1-76483]

Western Blot: Axin-1 AntibodyBSA Free [NBP1-76483]

Western Blot: Axin-1 Antibody [NBP1-76483] - SK-N-SH cell lysate with AXIN1 antibody at 1 ug/mL.

Applications for Axin-1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Axin-1

AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.

Long Name

Axis Inhibitor 1

Alternate Names

Axin1, MGC52315

Gene Symbol

AXIN1

UniProt

AAC51624 (Human)

Additional Axin-1 Products

Product Documents for Axin-1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Axin-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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