Axl Antibody - Humanized, (Research Grade mipasetamAb Biosimilar)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28443

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1

Concentration

LYOPH mg/ml

View all Axl Antibodies »

Product Specifications

Immunogen

AXL / UFO

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'mipasetamAb'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Axl Antibody - Humanized, (Research Grade mipasetamAb Biosimilar)

Axl Antibody - Humanized, (Research Grade mipasetamAb Biosimilar)

Flow Cytometry: CHO Axl mAb (mipasetamAb) - Humanized [NBP3-28443]

Flow Cytometry: CHO Axl mAb (mipasetamAb) - Humanized [NBP3-28443] - Axl expression on human monocyte-derived macrophages. The macrophages were treated with Axl PE (mipasetamab) antibody (blue), diluted 1:100, or human IgG1 PE isotype control antibody (red) for 30 minutes on ice. Image from a verified customer review. The customer used the PE-conjugated version of NBP3-28443, which is listed under NBP3-28443PE.

Applications for Axl Antibody - Humanized, (Research Grade mipasetamAb Biosimilar)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Axl

Axl is encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Long Name

Axl Receptor Tyrosine Kinase

Alternate Names

AI323647, ARK, JTK11, Tyro7, UFO

Gene Symbol

AXL

UniProt

P30530 (Human)

Additional Axl Products

Product Documents for Axl Antibody - Humanized, (Research Grade mipasetamAb Biosimilar)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Axl Antibody - Humanized, (Research Grade mipasetamAb Biosimilar)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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