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B4GALT7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00011285-B01P

Novus Biologicals, part of Bio-Techne
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H00011285-B01P

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

B4GALT7 (NP_009186.1, 1 a.a. - 327 a.a.) full-length human protein. MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARAVRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLSRKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTALSVGGAPCTVLNIMLDCDKTATPWCTFS

Specificity

B4GALT7 - xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I),

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for B4GALT7 Antibody

Western Blot: B4GALT7 Antibody [H00011285-B01P]

Western Blot: B4GALT7 Antibody [H00011285-B01P]

Western Blot: B4GALT7 Antibody [H00011285-B01P] - Analysis of B4GALT7 expression in HepG2.
Western Blot: B4GALT7 Antibody [H00011285-B01P]

Western Blot: B4GALT7 Antibody [H00011285-B01P]

Western Blot: B4GALT7 Antibody [H00011285-B01P] - Analysis of B4GALT7 expression in transfected 293T cell line by B4GALT7 polyclonal antibody. Lane 1: B4GALT7 transfected lysate(35.97 KDa). Lane 2: Non-transfected lysate.

Applications for B4GALT7 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: B4GALT7

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) linkage found in proteoglycans. Manganese is required as a cofactor. This enzyme differs from the other six beta4GalTs because it lacks the conserved beta4GalT1-beta4GalT6 Cys residues and it is located in cis-Golgi instead of trans-Golgi. Two single-nucleotide mutations were identified from a patient with the progeroid type of Ehlers-Danlos syndrome. [provided by RefSeq]

Long Name

UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 7

Alternate Names

b4Gal-T7, beta-1,4-galactosyltransferase 7, Beta-1,4-GalTase 7, beta4Gal-T7, beta4GalT-VII, EC 2.4.1.-, EDSP1, EDSSLA, EDSSPD1, proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7, XGALT1, XGALT-1, XGALT1beta-1,4-galactosyltransferase VII, XGPT, XGPT1, xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7(galactosyltransferase I)

Entrez Gene IDs

11285 (Human)

Gene Symbol

B4GALT7

Additional B4GALT7 Products

Product Documents for B4GALT7 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for B4GALT7 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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