Bag-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25295

Novus Biologicals, part of Bio-Techne
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NBP3-25295
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Bag-1 Antibodies »

Product Summary for Bag-1 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Bag-1 using the following amino acid sequence: AAGLTVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Bag-1 Antibody

Bag-1 Antibody Immunocytochemistry/Immunofluorescence: Bag-1 Antibody [NBP3-25295]

Immunocytochemistry/Immunofluorescence: Bag-1 Antibody [NBP3-25295]

Staining of human cell line SiHa shows localization to nucleoplasm.

Applications for Bag-1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Bag-1

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.

Long Name

Bcl-2-associated Anthanogene-1

Alternate Names

Bag1

Gene Symbol

BAG1

Additional Bag-1 Products

Product Documents for Bag-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Bag-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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