BAK Antibody (38E2) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-74026B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-74026AF350

Alexa Fluor 405

NBP1-74026AF405

Alexa Fluor 488

NBP1-74026AF488

Alexa Fluor 532

NBP1-74026AF532

Alexa Fluor 594

NBP1-74026AF594

Alexa Fluor 647

NBP1-74026AF647

Alexa Fluor 700

NBP1-74026AF700

Alexa Fluor 750

NBP1-74026AF750

Allophycocyanin/Cy7

NBP1-74026APCCY7

CoraFluor 1

NBP1-74026CL1

DyLight 350

NBP1-74026UV

DyLight 405

NBP1-74026V

DyLight 488

NBP1-74026G

DyLight 550

NBP1-74026R

DyLight 594

NBP1-74026DL594

DyLight 650

NBP1-74026C

DyLight 680

NBP1-74026FR

DyLight 755

NBP1-74026IR

FITC

NBP1-74026F

HRP

NBP1-74026H

Janelia Fluor 525

NBP1-74026JF525

Janelia Fluor 549

NBP1-74026JF549

Janelia Fluor 585

NBP1-74026JF585

Janelia Fluor 635

NBP1-74026JF635

Janelia Fluor 646

NBP1-74026JF646

Janelia Fluor 669

NBP1-74026JF669

mFluor Violet 450 SE

NBP1-74026MFV450

mFluor Violet 500 SE

NBP1-74026MFV500

mFluor Violet 610 SE

NBP1-74026MFV610

PE

NBP1-74026PE

PE/Atto594

NBP1-74026PEATT594

PE/Cy5.5

NBP1-74026PECY55

PE/Cy7

NBP1-74026PECY7

Forumulation

Catalog #

BSA Free

NBP1-74026

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 38E2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BAK Antibodies »

Product Summary for BAK Antibody (38E2) [Biotin]

Immunogen

Recombinant human BAK (29-187aa) purified from E.coli

Reactivity Notes

0

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Applications for BAK Antibody (38E2) [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BAK

Bak a pro-apoptotic analog to Bax, is a member of the Bcl-2 family of proteins. During mitochondria-regulated programmed cell death, Bak promotes apoptosis by binding Bcl-2 and inhibiting its anti-apoptotic function (1). Upon apoptotic stimulation, Bak translocates from the cytosol to the mitochondrial membrane (2). Pro-apoptotic cascade activates BID, which oligomerizes Bak into pores that result in the release of cytochrome c (2, 3). In healthy cells, Bak associate with Bcl-xL and Mcl-1 but not with Bcl-2, Bcl-w or A1 and only when freed of both Bak will induce apoptosis.

Long Name

Bcl-2 Antagonist/Killer

Alternate Names

BAK1, BCL2L7

Gene Symbol

BAK1

Additional BAK Products

Product Documents for BAK Antibody (38E2) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for BAK Antibody (38E2) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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