BBS4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-68873

Novus Biologicals, part of Bio-Techne
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NBP1-68873
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all BBS4 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EKQNWLIHLHYIRK corresponding to internal region (near N-Terminus) according to NP_149017.2.

Epitope

C-EKQNWLIHLHYIRK

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for BBS4 Antibody

Western Blot: BBS4 Antibody [NBP1-68873]

Western Blot: BBS4 Antibody [NBP1-68873]

Western Blot: BBS4 Antibody [NBP1-68873] - NBP1-68873 (1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for BBS4 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:1000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 65 kDa band observed in human testis lysates (calculated MW of 58.3 kDa band according to NP_149017.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BBS4

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.

Alternate Names

Bardet-Biedl syndrome 4, Bardet-Biedl syndrome 4 protein

Entrez Gene IDs

585 (Human); 102774 (Mouse)

Gene Symbol

BBS4

UniProt

NP_149017.2 (Human)

Additional BBS4 Products

Product Documents for BBS4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BBS4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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